A new study from the lab examines how non-coding regions of the genome contribute to the regulation of gene expression. While these regions do not encode proteins, they play a critical role in controlling when and where genes are active. The research focuses on identifying regulatory elements that influence transcriptional outcomes. Using genomic mapping and […]
In a collaborative study, the lab investigated how DNA regulatory elements function across different cell types. Gene regulation is highly context-dependent, and understanding these differences is essential for interpreting genomic data. The study compared regulatory activity in multiple cellular systems. Researchers identified regulatory elements that are shared across cell types as well as those that […]
The lab is using long-read sequencing technologies to study regions of the genome that are difficult to analyze with traditional methods. These regions often contain repeats or structural complexity that obscures accurate variant detection. Long-read data provides a clearer view of genome structure. By applying this technology, researchers were able to resolve complex rearrangements and […]
The lab has developed improved methods for studying DNA repair pathways in human cells. These approaches allow researchers to track how cells respond to DNA damage and identify key factors involved in maintaining genome integrity. The work addresses long-standing challenges in measuring repair activity at high resolution. By combining molecular assays with genomic analysis, the […]